r-bioc-demixt

Cell type-specific deconvolution of heterogeneous tumor samples

Description

When studying cancer cells from tumors excised from patients, the samples will be a mixture of tumors and healthy cells, e.g. from invading immune cells. For comparing samples, the interest may be more on comparing the transcriptome of the tumors themselves.

This package prepares the statistical separation (deconvolution) of RNAseq or microarray generated expression data for two or three components.

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Homepage

https://bioconductor.org/packages/DeMixT/


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