emmax

genetic mapping considering population structure

Description

EMMAX is a statistical test for large scale human or model organism association mapping accounting for the sample structure. In addition to the computational efficiency obtained by EMMA algorithm, EMMAX takes advantage of the fact that each locus explains only a small fraction of complex traits, which allows one to avoid repetitive variance component estimation procedure, resulting in a significant amount of increase in computational time of association mapping using mixed model.

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Homepage

http://genome.sph.umich.edu/wiki/EMMAX


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