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compute the melting temperature of nucleic acid duplex

compute the melting temperature of nucleic acid duplex
from version 4.3.1+dfsg-1


This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough.

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3400 other people were interested in this package here. The newest known version of this software is 5.2.0-2 (Information last updated about 7 hours ago.)