pbgenomicconsensus

Description

The GenomicConsensus package provides Quiver, Pacific Biosciences' flagship consensus and variant caller. Quiver is an algorithm that finds the maximum likelihood template sequence given PacBio reads of the template. These reads are modeled using a conditional random field approach that prescribes a probability to a read given a template sequence. In addition to the base sequence of each read, Quiver uses several additional quality value covariates that the base caller provides.

This package is part of the SMRTAnalysis suite

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Homepage

https://github.com/PacificBiosciences/GenomicConsensus

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