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secondary structure and solvent accessibility predictor


This package provides prof(1), the protein secondary structure, accessibility and transmembrane helix predictor from Burkhard Rost. Prediction is either done from protein sequence alone or from an alignment - the latter should be used for optimal performance.

How well does prof(1) perform?

 * Secondary structure is predicted at an expected average accuracy > 72% for
   the three states helix, strand and loop.

 * Solvent accessibility is predicted at a correlation coefficient
   (correlation between experimentally observed and predicted relative
   solvent accessibility) of 0.54

 * Transmembrane helix prediction has an expected per-residue accuracy of
   about 95%. The number of false positives, i.e., transmembrane helices
   predicted in globular proteins, is about 2%.

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1595 other people were interested in this package here. The newest known version of this software is 1.0.42-3 (Information last updated 9 minutes ago.)