python3-pairtools-examples
Process sequencing data from a Hi-C experiment (examples)
Description
Simple and fast command-line framework to process sequencing data from a Hi-C experiment. Process pair-end sequence alignments and perform the following operations: - Detect ligation junctions (a.k.a. Hi-C pairs) in aligned paired-end
sequences of Hi-C DNA molecules
- Sort .pairs files for downstream analyses
- Detect, tag and remove PCR/optical duplicates
- Generate extensive statistics of Hi-C datasets
- Select Hi-C pairs given flexibly defined criteria
- Restore .sam alignments from Hi-C pairs
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Homepage
https://github.com/mirnylab/pairtools
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