QUality Optimized Reads of genomic sequences


QuorUM enables to obtain trimmed and error-corrected reads that result in assemblies with longer contigs and fewer errors. QuorUM provides best performance compared to other published error correctors in several metrics. QuorUM is efficiently implemented making use of current multi- core computing architectures and it is suitable for large data sets (1 billion bases checked and corrected per day per core). The third-party assembler (SOAPdenovo) benefits significantly from using QuorUM error- corrected reads. QuorUM error corrected reads result in a factor of 1.1 to 4 improvement in N50 contig size compared to using the original reads with SOAPdenovo for the data sets investigated.

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