GRO-seq Analysis Pipeline
DescriptionThis BioConductor package provides a pipeline for the analysis of GRO- seq data. Among the more advanced features, r-bioc-grohmm predicts the boundaries of transcriptional activity across the genome de novo using a two-state hidden Markov model (HMM). The used model essentially divides the genome into transcribed and non- transcribed regions in a strand specific manner. HMMs are used to identify the leading edge of Pol II at genes activated by a stimulus in GRO-seq time course data. This approach allows the genome-wide interrogation of transcription rates in cells.
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Install this software package
If the package is available for the distribution you are currently using on your computer then install the software by clicking on…Install r-bioc-grohmm