r-cran-sctransform

Variance Stabilizing Transformations for Single Cell UMI Data

Description

A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija 2019 <doi:10.1101/576827> for more details.

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Homepage

https://cran.r-project.org/package=sctransform


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