post-processing of high-throughput DNA sequence reads


skewer implements the bit-masked k-difference matching algorithm dedicated to the task of adapter trimming and it is specially designed for processing next-generation sequencing (NGS) paired-end sequences.


 * Detection and removal of adapter sequences
 * Insertion and deletion allowed in pattern matching
 * Targeted at Single End, Paired End (PE), and Long Mate Pair (LMP) reads
 * Demultiplexing of barcoded sequencing runs
 * Multi-threading support
 * Trimming based on phred quality scores
 * IUPAC characters for barcodes and adapters
 * Compressed input and output support

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Install skewer