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Find statistically significant patterns in sequences


Smile determines sequence motifs on the basis of a set of DNA, RNA or protein sequences.
 * No hard limit on the number of combinations of motifs to describe
   subsets of sequences.
 * The sequence alphabet may be specified.
 * The use of wildcards is supported.
 * Better determination of significance of motifs by simulation.
 * Introduction of a set of sequences with negative controls
   that should not match automatically determined motifs.


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