r-bioc-dnacopy

Description

Implements the circular binary segmentation (CBS) algorithm to segment DNA copy number data and identify genomic regions with abnormal copy number.

This package is for analyzing array DNA copy number data, which is usually (but not always) called array Comparative Genomic Hybridization (array CGH) data It implements a methodology for finding change-points in these data which are points after which the (log) test over reference ratios have changed location. This model is that the change-points correspond to positions where the underlying DNA copy number has changed. Therefore, change-points can be used to identify regions of gained and lost copy number. Also provided is a function for making relevant plots of these data.

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Homepage

https://www.bioconductor.org/packages/DNAcopy/

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