sourmash

tools for comparing DNA sequences with MinHash sketches

Description

Compute MinHash signatures for nucleotide (DNA/RNA) and protein sequences.

MinHash sketches provide a lightweight way to store “signatures” of large DNA or RNA sequence collections, and then compare or search them using a Jaccard index. MinHash sketches can be used to identify samples, find similar samples, identify data sets with shared sequences, and build phylogenetic trees (Ondov et al. 2015).

sourmash provides a command line script, a Python library, and a CPython module for MinHash sketches.

These tools provide functionality previously handled by the 'khmer' package.

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Homepage

https://github.com/dib-lab/sourmash


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