tools for working with genome variation graphs


variation graph data structures, interchange formats, alignment, genotyping, and variant calling methods

Variation graphs provide a succinct encoding of the sequences of many genomes. A variation graph (in particular as implemented in vg) is composed of:

 - nodes, which are labeled by sequences and ids
 - edges, which connect two nodes via either of their respective ends
 - paths, describe genomes, sequence alignments, and annotations (such as gene
  models and transcripts) as walks through nodes connected by edges

This model is similar to a number of sequence graphs that have been used in assembly and multiple sequence alignment. Paths provide coordinate systems relative to genomes encoded in the graph, allowing stable mappings to be produced even if the structure of the graph is changed.

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Install vg